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Ovarian Reserve Panel

Summary
Ovarian Reserve describes the ovary's capacity to respond to gonadotropin stimulation by producing a sufficient number of good quality eggs capable of generating normal embryos. Inhibin-B serum concentration provides a new measure of ovarian reserve to accompany the measurement of day 3 follicle stimulating hormone (FSH) and estradiol (E2) concentrations.

Some studies have shown that the day 3 FSH/LH ratio has been useful in predicting ovarian response to gonadotropin stimulation. Since inhibin-B is secreted by granulosa cells and controls FSH secretion from the pituitary gland, it is a more direct measurement of assessing follicular function than FSH.

Inhibin-B serum concentrations drawn on day 3 have also been shown to predict response of ovaries to gonadotropin stimulation in IVF cycles. Women who had less than 45 pg/ml Inhibin-B on cycle day 3 had a 70% reduction in pregnancy rate than women with day 3 inhibin concentrations greater than 45pg/ml.

Women with anti-ovarian antibodies are less likely to become pregnant after IVF/ET than women without anti-ovarian antibodies. The predictive value of a positive anti-ovarian antibody for poor pregnancy outcome after IVF/ET is 82%.

Panel Tests Included
Inhibin-B, anti-ovarian antibodies (AOA), FSH, LH and E2.

Specimen Collection and Shipping Requirements

  • Collect three (3) 10 ml red or tiger top tubes.
  • Ship at room temperature in prepaid FedEx mailers overnight, next day morning.

Turn Around Time
Processing of specimens begins immediately upon receipt at our facilities. Results are routinely available within 7 to 10 days and are initially faxed, then mailed to the requesting physician.

Cost
Included in our fees are specimen collection and shipping materials, all courier and shipping charges, telephone and written reports, and consultation with physicians. Please call (312) 274-1928 for pricing information.

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